Transcription factor AP-2-alpha Recombinant Rabbit Monoclonal Antibody [PSH02-05]

Transcription factor AP-2-alpha Recombinant Rabbit Monoclonal Antibody [PSH02-05]

• Description: Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region.
• Product Name Alternative: Activating enhancer binding protein 2 alpha antibody Activating enhancer-binding protein 2-alpha antibody Activator protein 2 antibody AP 2 transcription factor antibody AP 2alpha antibody AP-2 antibody AP-2 transcription factor antibody AP2 antibody AP2 Transcription Factor antibody AP2-alpha antibody AP2A_HUMAN antibody AP2TF antibody BOFS antibody FLJ51761 antibody TFAP 2 antibody TFAP 2A antibody TFAP2 antibody TFAP2A antibody Transcription factor AP 2 alpha (activating enhancer binding protein 2 alpha) antibody Transcription factor AP-2-alpha antibody Transcription factor AP2 alpha antibody
• Abbreviation: TFAP2A, AP2TF, TFAP2
• CAS Number: 9000-83-3
• Swiss Prot: P05549 Human, P34056 Mouse, P58197 Rat
• Cellular Locus: Nucleus.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Recombinant protein within human TFAP2A aa 1-437 / 437.
• Isotype: IgG
• Clone: PSH02-05
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IHC-P, IF-Cell
• Positive Control: JAR cell lysate, HepG2 cell lysate, SiHa cell lysate, HepG2, human breast tissue, mouse eye tissue, rat breast tissue, rat skin tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000 ;IHC-P: 1:200-1:1,000 ;IF-Cell: 1:100
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 48 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes