Transcription factor AP-2-alpha Recombinant Rabbit Monoclonal Antibody [PSH02-06]

• Description:

  Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region.

• Product Name Alternative:

  Activating enhancer binding protein 2 alpha antibody Activating enhancer-binding protein 2-alpha antibody Activator protein 2 antibody AP 2 transcription factor antibody AP 2alpha antibody AP-2 antibody AP-2 transcription factor antibody AP2 antibody AP2 Transcription Factor antibody AP2-alpha antibody AP2A_HUMAN antibody AP2TF antibody BOFS antibody FLJ51761 antibody TFAP 2 antibody TFAP 2A antibody TFAP2 antibody TFAP2A antibody Transcription factor AP 2 alpha (activating enhancer binding protein 2 alpha) antibody Transcription factor AP-2-alpha antibody Transcription factor AP2 alpha antibody

• Abbreviation:

  TFAP2A, AP2TF, TFAP2

• Swiss Prot:

  P05549 Human

• Cellular Locus:

  Nucleus.

• Host:

  Rabbit

• Species Reactivity:

  Human

• Immunogen:

  Recombinant protein within human TFAP2A aa 1-437 / 437.

• Isotype:

  IgG

• Clone:

  PSH02-06

• Conjugation:

  Non-conjugated

• Type:

  Recombinant Rabbit monoclonal Antibody

• Applications:

  WB, IHC-P, IF-Cell

• Positive Control:

  HepG2 cell lysate, SiHa cell lysate, HepG2, human breast tissue.

• Concentration:

  1 mg/mL

• Dilution:

  WB: 1:1,000 ;IHC-P: 1:1,000 ;IF-Cell: 1:100

• Purity:

  Protein A affinity purified.

• Form:

  Liquid

• Buffer:

  PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  Predicted band size: 48 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

• Recombinant Antibody:

  Yes

• CAS Number:

  9000-83-3