Fibronectin Mouse mAb

• Background:

  Fibronectin is a high-molecular weight glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins. Similar to integrins, fibronectin binds extracellular matrix components such as collagen.Fibronectin exists as a protein dimer, consisting of two nearly identical monomers linked by a pair of disulfide bonds. The fibronectin protein is produced from a single gene, but alternative splicing of its pre-mRNA leads to the creation of several isoforms.

• Description:

  Fibronectin is a high-molecular weight glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins. Similar to integrins, fibronectin binds extracellular matrix components such as collagen. Fibronectin exists as a protein dimer, consisting of two nearly identical monomers linked by a pair of disulfide bonds. The fibronectin protein is produced from a single gene, but alternative splicing of its pre-mRNA leads to the creation of several isoforms.

• UniProt:

  P02751

• Swiss Prot:

  P02751

• Reactivity:

  Human, Rat, Mouse

• Immunogen:

  Synthetic Peptide

• Clonality:

  Monoclonal

• Source:

  Mouse

• Applications:

  WB, IHC

• Concentration:

  1mg/mL

• Dilution:

  WB 1:1,000-2,000 IHC 1:200-500

• Molecular Weight:

  285kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  285kDa

• Fragment:

  IgG1

• Subcellular Location:

  Secreted, extracellular space, extracellular matrix

• Other Product Names:

  CIG, Cold insoluble globulin, fibronectin 1, FN, fN1, FNZ, GFND, GFND2, UgI-Y3

• Gene ID (Human):

  2335