CD41/Integrin α/2b Mouse mAb

• Background:

  ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibrinogen receptor expressed in platelets that plays a crucial role in coagulation.

• Description:

  ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibrinogen receptor expressed in platelets that plays a crucial role in coagulation.

• Synonyms:

  BDPLT2, CD41 antigen, CD41a, gp2b, ITGA2B, platelet fibrinogen receptor alpha

• Gene ID:

  3674

• UniProt:

  P08514

• Cellular Locus:

  Membrane

• Host:

  Mouse

• Species Reactivity:

  Human

• Reactivity:

  Human

• Immunogen:

  Synthetic Peptide

• Clonality:

  Monoclonal

• Isotype:

  IgG1

• Source:

  Mouse

• Applications:

  IHC

• Validated Applications:

  IHC

• Stability:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Concentration:

  1 mg/mL

• Dilution:

  IHC 1:100-200

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Subcellular Location:

  Membrane

• Other Product Names:

  BDPLT2, CD41 antigen, CD41a, gp2b, ITGA2B, platelet fibrinogen receptor alpha

• Gene ID (Human):

  3674

• SwissProt (Human):

  P08514