CD5 Mouse mAb
CAT:
855-EM1071-02
Size:
100 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
CD5 Mouse mAb
- Description: CD5 is a cluster of differentiation found on a subset of IgM-secreting B cells called B-1 cells, and also on T cells. B-1 cells have limited diversity of their B-cell receptor due to their lack of the enzyme terminal deoxynucleotidyl transferase (TdT) and are potentially self-reactive. CD5 serves to mitigate activating signals from the BCR so that the B-1 cells can only be activated by very strong stimuli (such as bacterial proteins) and not by normal tissue proteins.
- Synonyms: CD5 molecule, LEU1, Lymphocyte antigen T1/Leu 1, T1
- Gene ID: 921
- UniProt: P06127
- Cellular Locus: Membrane
- Host: Mouse
- Species Reactivity: Human, Rat, Mouse
- Immunogen: Synthetic Peptide
- Clonality: Monoclonal
- Validated Applications: IHC
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: IHC 1:100-200
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.