CDX2 Mouse mAb
CAT:
855-EM1057-02
Size:
100 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
CDX2 Mouse mAb
- Description: CDX2 is a caudal type homeobox gene that encodes an intestine-specific transcription factor that is expressed early in intestinal development and may be involved in the regulation of proliferation and differentiation of intestinal epithelial cells. It is expressed in the nuclei of epithelial cells throughout the intestine, from duodenum to rectum. The CDX2 protein is expressed in primary and metastatic colorectal carcinomas and has also been demonstrated in the intestinal metaplasia of the stomach and intestinal-type gastric cancer, while it is not expressed in the normal gastric mucosa. Studies have shown that CDX2 is superior marker compared to CK20.
- Synonyms: Caudal Type Homeobox Transcription Factor 2 ;CDX3; Homeobox Protein CDX-2
- Gene ID: 1045
- UniProt: Q99626
- Cellular Locus: Nucleus
- Host: Mouse
- Species Reactivity: Human, Rat, Mouse
- Immunogen: Synthetic Peptide
- Clonality: Monoclonal
- Validated Applications: WB, IHC
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: WB 1:1,000 IHC 1:200
- Molecular Weight: 42kDa
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.