[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic polypeptide (TFA)

[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic polypeptide (TFA)

• UNSPSC Description: [cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide is a potent and selective neuropeptide Y Y5 receptor agonist with an IC50 of 0.24 nM for binding to the hY5 receptor. [cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide induces a high amount of food intake[1].
• Target Antigen: Neuropeptide Y Receptor
• Type: Peptides
• Related Pathways: GPCR/G Protein;Neuronal Signaling
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/cpp1-7-npy19-23-ala31-aib32-gln34-hpancreatic-polypeptide-tfa.html
• Solubility: H2O
• Smiles: O=C(CN)N1[C@H](C(N[C@H](C(N[C@H](C(N2[C@H](C(N[C@H](C(N[C@H](C(N3[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N4[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NC(C)(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CC5=CC=C(O)C=C5)=O)CCCNC(N)=N)=O)CCC(N)=O)=O)CCCNC(N)=N)=O)C)=O)C)=O)CCSC)=O)CC(N)=O)=O)[C@H](CC)C)=O)CC6=CC=C(O)C=C6)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CC(C)C)=O)C)=O)CO)=O)CC7=CC=C(O)C=C7)=O)CC8=CC=C(O)C=C8)=O)CCCNC(N)=N)=O)C)=O)CCSC)=O)CCC(N)=O)=O)CCC(O)=O)=O)CCC4)=O)[C@@H](C)O)=O)C)=O)CC(N)=O)=O)CC(O)=O)=O)=O)CCC3)=O)CC9=CC=C(O)C=C9)=O)[C@@H](C)O)=O)CCC2)=O)CCC(N)=O)=O)CO)=O)CCC1.O=C(O)C(F)(F)F
• Molecular Weight: 4321.68
• References & Citations: [1]C Cabrele , et al. The first selective agonist for the neuropeptide YY₅ receptor increases food intake in rats. J Biol Chem. 2000 Nov 17;275(46):36043-8.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported