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Nociceptin (1-7) (TFA)

CAT: 0804-HY-P1319ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P1319ASize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Nociceptin (1-7) TFA is the N-terminal bioactive fragment of nociceptin. Nociceptin (1-7) TFA is a potent ORL1 (NOP) receptor agonist with antinociceptive activity. Nociceptin (1-7) TFA combines with nociceptin reduces hyperalgesia in vivo[1].
UNSPSC
12352209
Target
Opioid Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/nociceptin-1-7-tfa.html
Solubility
10 mM in DMSO
Smiles
C[C@@H](C(O)=O)NC(CNC([C@H]([C@H](O)C)NC([C@H](CC1=CC=CC=C1)NC(CNC(CNC([C@H](CC2=CC=CC=C2)N)=O)=O)=O)=O)=O)=O.O=C(O)C(F)(F)F
Molecular Formula
C33H42F3N7O11
Molecular Weight
769.72
References & Citations
[1]T Sakurada, et al. Nociceptin (1-7) antagonizes nociceptin-induced hyperalgesia in mice.Br J Pharmacol. 1999 Nov;128 (5) :941-4.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
NOP Receptor/ORL1