Nociceptin(1-7) (TFA)

Nociceptin(1-7) (TFA)

• UNSPSC Description: Nociceptin (1-7) TFA is the N-terminal bioactive fragment of nociceptin (HY-P0183). Nociceptin (1-7) TFA is a potent ORL1?(NOP) receptor agonist with antinociceptive activity. Nociceptin (1-7) TFA combines with nociceptin reduces hyperalgesia in vivo[1].
• Target Antigen: Opioid Receptor
• Type: Peptides
• Related Pathways: GPCR/G Protein;Neuronal Signaling
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/nociceptin-1-7-tfa.html
• Solubility: 10 mM in DMSO
• Smiles: C[C@@H](C(O)=O)NC(CNC([C@H]([C@H](O)C)NC([C@H](CC1=CC=CC=C1)NC(CNC(CNC([C@H](CC2=CC=CC=C2)N)=O)=O)=O)=O)=O)=O.O=C(O)C(F)(F)F
• Molecular Weight: 769.72
• References & Citations: [1]T Sakurada, et al. Nociceptin (1-7) antagonizes nociceptin-induced hyperalgesia in mice.Br J Pharmacol. 1999 Nov;128(5):941-4.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported