Prilocaine

• Description :

  Prilocaine, an amino amide, is a Na/K-ATPase inhibitor. Prilocaine has neurotoxic effects[1][2].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Na+/K+ ATPase

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/prilocaine.html

• Purity :

  99.94

• Solubility :

  DMSO : 100 mg/mL (ultrasonic) |H2O : 2.5 mg/mL (ultrasonic)

• Smiles :

  CC(NCCC)C(NC1=CC=CC=C1C)=O

• Molecular Formula :

  C13H20N2O

• Molecular Weight :

  220.31

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]M Mete, et al. Neurotoxic effects of local anesthetics on the mouse neuroblastoma NB2a cell line. Biotech Histochem. 2015 Apr;90 (3) :216-22.|[2]H Kutchai, et al. Effects of local anaesthetics on the activity of the Na, K-ATPase of canine renal medulla. Pharmacol Res. 2000 Jan;41 (1) :1-7.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Launched

• CAS Number :

  [721-50-6]