Prilocaine

• Description:

  Prilocaine, an amino amide, is a Na/K-ATPase inhibitor. Prilocaine has neurotoxic effects[1][2].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Na+/K+ ATPase

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/prilocaine.html

• Purity:

  99.94

• Solubility:

  DMSO : 100 mg/mL (ultrasonic) |H2O : 2.5 mg/mL (ultrasonic)

• Smiles:

  CC(NCCC)C(NC1=CC=CC=C1C)=O

• Molecular Formula:

  C13H20N2O

• Molecular Weight:

  220.31

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]M Mete, et al. Neurotoxic effects of local anesthetics on the mouse neuroblastoma NB2a cell line. Biotech Histochem. 2015 Apr;90 (3) :216-22.|[2]H Kutchai, et al. Effects of local anaesthetics on the activity of the Na, K-ATPase of canine renal medulla. Pharmacol Res. 2000 Jan;41 (1) :1-7.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  Launched

• CAS Number:

  [721-50-6]