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2'-MeCCPA

CAT: 0804-HY-103180-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-103180-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
2'-MeCCPA is a potent and selective A1 adenosine receptors (A1AR) agonist. 2'-MeCCPA efficiently inhibits cAMP modulation in both direct pathway medium spiny neurons (dMSNs) and indirect pathway medium spiny neurons (iMSNs) [1][2].
CAS Number
205171-12-6
UNSPSC
12352005
Target
Adenosine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/2-meccpa.html
Purity
99.80
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
ClC1=NC2=C(C(NC3CCCC3)=N1)N=CN2[C@H]4[C@@](O)(C)[C@H](O)[C@@H](CO)O4
Molecular Formula
C16H22ClN5O4
Molecular Weight
383.83
References & Citations
[1]J Bhandal, et al. Adenosine a1 receptor activation can protect the myocardium from ischaemia reperfusion injury post reperfusion. BMJ Journals. Volume 104, Issue Suppl 3.|[2]Muntean BS, et al. Interrogating the Spatiotemporal Landscape of Neuromodulatory GPCR Signaling by Real-Time Imaging of cAMP in Intact Neurons and Circuits. Cell Rep. 2018 Jan 2;22 (1) :255-268.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Adenosine A1 receptor (A1R)

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