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Urumin

CAT: 0804-HY-P5550Size: 1 EachDry Ice: NoHazardous: No
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Description
Urumin has antiviral activity against the human influenza A virus. Urumin inhibits the growth of PR8 influenza virus (IC50: 3.8 μM) . Urumin targets the conserved stalk of H1 hemagglutini, and is effective at neutralizing drug-resistant H1 influenza viruses. Urumin protects naive mice from lethal influenza infection[1].
CAS Number
2215863-74-2
UNSPSC
12352209
Target
Influenza Virus
Type
Peptides
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/urumin.html
Solubility
10 mM in DMSO
Smiles
O=C(N1[C@@H](CCC1)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](C)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(N)=O)C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC3=CNC4=CC=CC=C34)C(N[C@@H](CC(O)=O)C(N[C@@H](CO)C(N[C@@H](CCC(N)=O)C(N[C@@H](CS)C(N[C@@H](CC5=CNC=N5)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC6=CC=CC=C6)C(N[C@@H](CO)C(N[C@@H](CC(N)=O)C(NCC(N[C@@H](C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](C)C(N[C@@H](CS)C(N[C@@H](C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H]([C@@H](C)CC)N
Molecular Formula
C129H198N42O35S2
Molecular Weight
2961.34
References & Citations
[1]Holthausen DJ, et al. An Amphibian Host Defense Peptide Is Virucidal for Human H1 Hemagglutinin-Bearing Influenza Viruses. Immunity. 2017 Apr 18;46 (4) :587-595.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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