YW3-56 (hydrochloride)

CAT:

26-B2858-500

Size:

500 µg

Price:

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Description: YW3-56 is an inhibitor of protein arginine deiminases PAD2 and PAD4 which convert protein arginine residues to citrulline. The IC₅₀ for inhibition of PAD4 and PAD2 is about 1–2 μM and 0.5–1 μM respectively. YW3-56 inhibits the growth of osteosarcoma U2OS cells with an IC₅₀ of 2.5 μM. YW3-56 induces p53 target genes SESN2 and DDIT4 which repress mTORC1 kinase activity. It perturbs autophagy and inhibits the growth of triple-negative breast cancer xenograft tumors in mice.
Shipping Conditions: Gel Pack
Storage Conditions: -20ºC
Shelf Life: 24months

Cat	Name
B2858-1000	YW3-56 (hydrochloride)
B2858-500	YW3-56 (hydrochloride)
B3051-5	RIPA-56
2592-25	AT 56
2592-5	AT 56
B3051-25	RIPA-56
B2708-250	Valganciclovir Hydrochloride
B2741-50	Sinomenine hydrochloride
B2815-1	CPTH2 (hydrochloride)
B2852-5	Resminostat (hydrochloride)

Cat	Name
MBS5784989-03	YW3-56 (hydrochloride)(technical grade)
T36107-5mg	YW3-56
MBS3844584-04	YW3-56
T36107-1g	YW3-56
T36107-50mg	YW3-56
T36108-50mg	YW3-56 (hydrochloride) (technical grade)
MBS3844584-03	YW3-56
MBS3844584-01	YW3-56
T36107-1mg	YW3-56
T36108-1mg	YW3-56 (hydrochloride) (technical grade)