Resminostat (hydrochloride)
CAT:
26-B2852-5
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Resminostat (hydrochloride)
- Description: Resminostat is a potent inhibitor of histone deacetylases (HDAC) 1, 3 and 6 with IC₅₀ ranging from 43–72 nM. It induces hyperacetylation of histone H4, abrogates cell growth and induces apoptosis in multiple myeloma cells with an IC₅₀ of 2.5-3 µM. It inhibits cell proliferation, induces G0/G1 cell cycle arrest, decreases levels of cyclin D1, cdc25a, Cdk4 and pRb and upregulates p21.
- Shipping Conditions: RT
- Storage Conditions: -20ºC
- Shelf Life: 36 months