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Resminostat (hydrochloride)

CAT: 0026-B2852-5Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0026-B2852-5Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Resminostat is a potent inhibitor of histone deacetylases (HDAC) 1, 3 and 6 with IC₅₀ ranging from 43–72 nM. It induces hyperacetylation of histone H4, abrogates cell growth and induces apoptosis in multiple myeloma cells with an IC₅₀ of 2.5-3 µM. It inhibits cell proliferation, induces G0/G1 cell cycle arrest, decreases levels of cyclin D1, cdc25a, Cdk4 and pRb and upregulates p21.
Shipping Conditions
RT
Storage Conditions
-20ºC
Shelf Life
36 months

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