Resminostat (hydrochloride)

CAT:

26-B2852-5

Size:

5 mg

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Description: Resminostat is a potent inhibitor of histone deacetylases (HDAC) 1, 3 and 6 with IC₅₀ ranging from 43–72 nM. It induces hyperacetylation of histone H4, abrogates cell growth and induces apoptosis in multiple myeloma cells with an IC₅₀ of 2.5-3 µM. It inhibits cell proliferation, induces G0/G1 cell cycle arrest, decreases levels of cyclin D1, cdc25a, Cdk4 and pRb and upregulates p21.
Shipping Conditions: RT
Storage Conditions: -20ºC
Shelf Life: 36 months

Cat	Name
B2852-25	Resminostat (hydrochloride)
B2852-5	Resminostat (hydrochloride)
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