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Ataciguat

CAT: 0026-B2574-5Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0026-B2574-5Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ataciguat is an anthranilic acid derivative that activates the oxidized (heme-free) form of soluble guanylate cyclase (sGC) (EC₅₀= 0.5-10 µM in purified bovine lung or crude human corpus cavernosum isolates) by binding to the heme pocket and mimicking its function. It has been shown to increase cGMP levels in cultured rat aorta smooth muscle cells and to induce vasorelaxation of isolated rat aorta, porcine coronary arteries, and human corpus cavernosum (EC₅₀ = 1-10 µM).
Shipping Conditions
Gel Pack
Storage Conditions
-20ºC
Shelf Life
36 months

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