AZ-304

CAT: 0026-B2571-25Size: 25 mgDry Ice: NoHazardous: No
CAT#:0026-B2571-25Size:25 mg
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AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AZ-304 is a potent, ATP-competitive dual BRAF kinase inhibitor that inhibits wild type BRAF, V600E mutant BRAF and wild type CRAF, with IC₅₀s of 79 nM, 38 nM and 68 nM, respectively. In addition, AZ-304 exhibits significant effect on other kinases such as p38 (IC₅₀, 6 nM), CSF1R (IC₅₀, 35 nM). AZ-304 exerts anti-tumour effects in colorectal cancer independently of BRAF genetic status.
Shipping Conditions
Gel Pack
Storage Conditions
-20ºC
Shelf Life
36 months

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