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iCRT14

CAT: 0026-B2562-5Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0026-B2562-5Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
iCRT14 is a potent potent inhibitor of β-catenin-responsive transcription (CRT) that inhibits Wnt signaling in a reporter assay in vitro (IC₅₀ = 40.3 nM). It inhibits the interaction between β-catenin and T cell factor 4 (Tcf4) in quantitative reporter assays of β-catenin/Tcf4 binding (Ki = 53.51 μM). It inhibits Notch, hedgehog (Hh), and JAK/STAT signaling in reporter assays with IC50 values of 69.2, 194, and 70 nM, respectively.
Shipping Conditions
Gel Pack
Storage Conditions
-20ºC
Shelf Life
36 months

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S8704-25mgICRT14