AZD-3229

• Description :

  AZD3229 is a potent, pan-KIT mutant inhibitor that displays single digit nM growth inhibition against a diverse panel of mutant KIT driven Ba/F3 cell lines (GI50=1-50 nM). It also inhibits PDGFR mutants (Tel-PDGFRα, Tel-PDGFRβ, V561D/D842V). Potentially could be useful for the treatment of gastrointestinal stromal tumors.

• Shipping Conditions :

  Gel Pack

• Storage Conditions :

  -20ºC

• Shelf Life :

  36 months