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Cyromazine

CAT: 0804-HY-B1331-01Size: 5 gDry Ice: NoHazardous: No
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CAT#:0804-HY-B1331-01Size:5 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cyromazine (CGA-72662) is a triazine insect growth regulator used as an insecticide and an acaricide. It is a cyclopropyl derivative of melamine. Cyromazine works by affecting the nervous system of the immature larval stages of certain insects. Cyromazine reduced the number of germ cells by interfering with the Ecdysone signaling pathway. Cyromazine induces renal toxicity attenuated and restored by green tea extract in rats[1][2][3][4][5].
CAS Number
66215-27-8
Product Name Alternative
Cyromazin; CGA-72662
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite; Parasite
Type
Natural Products
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Cyromazine.html
Purity
99.79
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
NC1=NC(N)=NC(NC2CC2)=N1
Molecular Formula
C6H10N6
Molecular Weight
166.18
Precautions
H302, H315, H319, H335
References & Citations
[1]Levot GW, et al. Survival advantage of cyromazine-resistant sheep blowfly larvae on dicyclanil- and cyromazine-treated Merinos. Aust Vet J. 2014 Nov;92 (11) :421-6.|[2]Khalid MZ, et al. Cyromazine Effects the Reproduction of Drosophila by Decreasing the Number of Germ Cells in the Female Adult Ovary[J]. Insects. 2022 Apr 27;13 (5) :414.|[3]T. Heikal, A. Mossa, et al. Cyromazine and Chlorpyrifos Induced Renal Toxicity in Rats: The Ameliorated Effects of Green Tea Extract[J]. Journal of Environmental and Analytical Toxicology. 2012 June 9; 2 (5) : 1000146.|[4]Khalid MZ, et al. Cyromazine affects the ovarian germ cells of Drosophila via the ecdysone signaling pathway[J]. Front Physiol. 2022 Sep 29;13:992306.|[5]TAREK M.HEIKAL, et al. The ameliorating effects of green tea extract against cyromazine and chlorpyrifos induced liver toxicity in male rats[J]. Asian Journal of Pharmaceutical and Clinical Research. 2013 January; 6 (1) :47-55.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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