Carbaryl-d3

• Description :

  Carbaryl-d3 is the deuterium labeled Carbaryl (HY-B1315) . Carbaryl is the inhibitor for acetylcholinesterase that inhibits the degradation of acetylcholine in the synaptic cleft, leads to the accumulation of acetylcholine and causes neurotoxicity. Carbaryl can be used as an insecticide[1][2]. X

• CAS Number :

  [1433961-56-8]

• UNSPSC :

  12352005

• Target :

  Apoptosis; Cholinesterase (ChE) ; Insecticide; Isotope-Labeled Compounds; Reactive Oxygen Species (ROS)

• Type :

  Isotope-Labeled Compounds

• Related Pathways :

  Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB; Others

• Field of Research :

  Inflammation/Immunology; Neurological Disease

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(OC1=C2C=CC=CC2=CC=C1)NC([2H])([2H])[2H]

• Molecular Formula :

  C12H8D3NO2

• Molecular Weight :

  204.24

• References & Citations :

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-223.|[2]Nancy E Todd, et al. Effects of Sevin (Carbaryl Insecticide) on Early Life Stages of Zebrafish (Danio Rerio) . Ecotoxicol Environ Saf. 2002 Oct;53 (2) :267-72.|[3]Blevins RD, et al., Effects of carbaryl and dieldrin on the growth, protein content, and phospholipid content of HeLa cells. J Agric Food Chem. 1975 May-Jun;23 (3) :377-82.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported