Carbaryl

CAT: 0804-HY-B1315-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0804-HY-B1315-01Size:25 mg
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Description
Carbaryl is the inhibitor for acetylcholinesterase that inhibits the degradation of acetylcholine in the synaptic cleft, leads to the accumulation of acetylcholine and causes neurotoxicity. Carbaryl can be used as an insecticide[1][2].
CAS Number
[63-25-2]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335, H350, H360
Target
Apoptosis; Cholinesterase (ChE) ; Insecticide; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB; Others
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/carbaryl.html
Concentration
10mM
Purity
99.95
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(OC1=C2C=CC=CC2=CC=C1)NC
Molecular Formula
C12H11NO2
Molecular Weight
201.22
Precautions
H302, H315, H319, H335, H350, H360
References & Citations
[1]Nancy E Todd, et al. Effects of Sevin (Carbaryl Insecticide) on Early Life Stages of Zebrafish (Danio Rerio) . Ecotoxicol Environ Saf. 2002 Oct;53 (2) :267-72.|[2]Blevins RD, et al., Effects of carbaryl and dieldrin on the growth, protein content, and phospholipid content of HeLa cells. J Agric Food Chem. 1975 May-Jun;23 (3) :377-82.|[3]Schock EN, et al., The effects of carbaryl on the development of zebrafish (Danio rerio) embryos. Zebrafish. 2012 Dec;9 (4) :169-78.|[4]Muthaiah VP, et al., Neuroprotective role of naringenin on carbaryl induced neurotoxicity in mouse neuroblastoma cells. J Pharmacol Pharmacother. 2013 Jul;4 (3) :192-7.|[5]Jorsaraei SG, et al., Immunotoxicity effects of carbaryl in vivo and in vitro. Environ Toxicol Pharmacol. 2014 Nov;38 (3) :838-44.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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