Hydroxyzine (dihydrochloride) (Standard)

• UNSPSC Description:

  Hydroxyzine (dihydrochloride) (Standard) is the analytical standard of Hydroxyzine (dihydrochloride). This product is intended for research and analytical applications. Hydroxyzine dihydrochloride, a benzodiazepine antihistamine agent, acts as a orally active histamine H1-receptor and serotonin antagonist. Hydroxyzine dihydrochloride has anxiolytic effect and can be used forthe research of generalised anxiety disorder[1][2].

• Target Antigen:

  Histamine Receptor

• Type:

  Reference Standards

• Related Pathways:

  GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling

• Field of Research:

  Inflammation/Immunology; Endocrinology

• Assay Protocol:

  https://www.medchemexpress.com/hydroxyzine-dihydrochloride-standard.html

• Smiles:

  ClC1=CC=C(C=C1)C(C2=CC=CC=C2)N3CCN(CCOCCO)CC3.Cl.Cl

• Molecular Weight:

  447.83

• References & Citations:

  [1]Minogiannis, P., et al., Hydroxyzine inhibits neurogenic bladder mast cell activation. Int J Immunopharmacol, 1998. 20(10): p. 553-63.|[2]Morichi, R. and G. Pepeu, A study of the influence of hydroxyzine and diazepam on morphine antinociceptoion in the rat. Pain, 1979. 7(2): p. 173-80.|[3]Nikita Shekhar Sawantdesai, et al. Evaluation of anxiolytic effects of aripiprazole and hydroxyzine as a combination in mice. J Basic Clin Pharm. 2016 Sep;7(4):97-104.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  Launched

• CAS Number:

  2192-20-3