AZD 5153

• Description:

  orally available, bivalent inhibitor of the bromodomain and extraterminal (BET) protein BRD4.

• Product Name Alternative:

  (3R)-4-[2-[4-[1-(3-methoxy-1,2,4-triazolo[4,3-b]pyridazin-6-yl)-4-piperidinyl]phenoxy]ethyl]-1,3-dimethyl-2-piperazinone

• Field of Research:

  Chromatin Epigenetics Bromodomain

• Purity:

  ≥95.00%

• Form:

  A crystalline solid

• Solubility:

  ≤20mg/ml in ethanol;20mg/ml in DMSO;20mg/ml in dimethyl formamide

• Smiles:

  COC1=NN=C2N1N=C(N3CCC(C4=CC=C(OCCN5[C@H](C)C(N(C)CC5)=O)C=C4)CC3)C=C2

• Molecular Formula:

  C25H33N7O3

• Molecular Weight:

  479.6

• Shipping Conditions:

  Blue ice

• Storage Conditions:

  Store at -20°C.

• CAS Number:

  1869912-39-9