MCC950

MCC950

• Product Name Alternative: CP-456773; CRID3
• CAS Number: 210826-40-7
• UNSPSC Description: MCC950 (CP-456773; CRID3) is a potent and selective NLRP3 inhibitor with IC50s of 7.5 and 8.1 nM in BMDMs and HMDMs, respectively.
• Target Antigen: NOD-like Receptor (NLR)
• Type: Reference compound
• Related Pathways: Immunology/Inflammation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/MCC950.html
• Purity: 99.62
• Solubility: DMSO : 83.33 mg/mL (ultrasonic)|H2O : 7.14 mg/mL (ultrasonic;warming;adjust pH to 11 with 1 M NaOH)
• Smiles: O=S(C1=CC(C(C)(O)C)=CO1)(NC(NC2=C3CCCC3=CC4=C2CCC4)=O)=O
• Molecular Weight: 404.48
• References & Citations: [1]Coll RC, et al. A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases. 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• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported