KPT-9274

• Description:

  Orally acitve allosteric inhibitor of PAK4

• Product Name Alternative:

  (1Z,2E)-3-(6-aminopyridin-2-yl)-N-((5-(4-(4,4-difluoropiperidine-1-carbonyl)phenyl)-7-(4-fluorophenyl)benzofuran-2-yl)methyl)acrylimidic acid

• Field of Research:

  Cell Cycle Checkpoint PAK4

• Purity:

  0.9942

• Form:

  A solid

• Solubility:

  ≥22.45 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH

• Smiles:

  FC1=CC=C(C2=CC(C3=CC=C(C(N4CCC(F)(F)CC4)=O)C=C3)=CC5=C2OC(C/N=C(O)/C([H])=C([H])/C6=NC(N)=CC=C6)=C5)C=C1

• Molecular Formula:

  C35H29F3N4O3

• Molecular Weight:

  610.62

• Shipping Conditions:

  Blue ice

• Storage Conditions:

  Store at -20°C.

• CAS Number:

  1643913-93-2