KPT-276

• Description:

  inhibitor of nuclear export (SINE) and CRM1, orally bioavailable

• Product Name Alternative:

  (Z)-3-[3-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-triazol-1-yl]-1-(3,3-difluoroazetidin-1-yl)prop-2-en-1-one

• Field of Research:

  Cell Cycle Checkpoint CRM1

• Purity:

  0.9997

• Form:

  A solid

• Solubility:

  insoluble in EtOH; insoluble in H2O; ≥19.85 mg/mL in DMSO

• Smiles:

  C1C(CN1C(=O)C=CN2C=NC(=N2)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)(F)F

• Molecular Formula:

  C16H10F8N4O

• Molecular Weight:

  426.26

• Shipping Conditions:

  Blue ice

• Storage Conditions:

  Store at -20°C.

• CAS Number:

  1421919-75-6