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Sulindac (Standard)

CAT: 0804-HY-B0008R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0008R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Sulindac (Standard) is the analytical standard of Sulindac. This product is intended for research and analytical applications. Sulindac (MK-231) is an orally active nonsteroidal anti-inflammatory agent. Sulindac also is an immunomodulatory agent. Sulindac can be used for the research of arthritis of the spine, gouty arthritis and kinds of cancer including colorectal cancer (CRC) and lung cancer[1][2].
CAS Number
38194-50-2
Product Name Alternative
MK-231 (Standard)
UNSPSC
12352005
Target
NF-κB; PD-1/PD-L1; Reference Standards
Type
Reference Standards
Related Pathways
Immunology/Inflammation; NF-κB; Others
Field of Research
Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/sulindac-standard.html
Smiles
O=C(CC(C1=C2C=CC(F)=C1)=C(/C2=C/C3=CC=C(C=C3)S(C)=O)C)O
Molecular Formula
C20H17FO3S
Molecular Weight
356.41
References & Citations
[1]Byong-Ki Cha, et al. Celecoxib and sulindac inhibit TGF-β1-induced epithelial-mesenchymal transition and suppress lung cancer migration and invasion via downregulation of sirtuin 1. Oncotarget. 2016 Aug 30;7 (35) :57213-57227. |[2]Bin Yi, et al. Sulindac Modulates the Response of Proficient MMR Colorectal Cancer to Anti-PD-L1 Immunotherapy. Mol Cancer Ther. 2021 Jul;20 (7) :1295-1304.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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