VX-745

• Description:

  P38α inhibitor,highly potent and selective

• Product Name Alternative:

  5-(2,6-dichlorophenyl)-2-(2,4-difluorophenyl)sulfanylpyrimido[1,6-b]pyridazin-6-one

• Field of Research:

  MAPK Signaling p38

• Purity:

  0.9919

• Form:

  A solid

• Solubility:

  ≥21.8 mg/mL in DMSO; insoluble in H2O; ≥2.1 mg/mL in EtOH with gentle warming and ultrasonic

• Smiles:

  C1=CC(=C(C(=C1)Cl)C2=C3C=CC(=NN3C=NC2=O)SC4=C(C=C(C=C4)F)F)Cl

• Molecular Formula:

  C19H9Cl2F2N3OS

• Molecular Weight:

  436.27

• Shipping Conditions:

  Blue ice

• Storage Conditions:

  Store at -20°C.

• CAS Number:

  209410-46-8