Pemetrexed

• Description:

  TS, DHFR,GARFT and AICARFT inhibitor

• Product Name Alternative:

  disodium;(2S)-2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioate

• Sequence:

  Pemetrexed disodium, LY-231514, Pemetrexed Na

• Field of Research:

  Metabolism DHFR Apoptosis Thymidylate Synthase

• Purity:

  0.9986

• Form:

  A solid

• Solubility:

  insoluble in EtOH; ≥15.68 mg/mL in DMSO with gentle warming and ultrasonic; ≥30.67 mg/mL in H2O

• Smiles:

  C1=CC(=CC=C1CCC2=CNC3=C2C(=O)N=C(N3)N)C(=O)NC(CCC(=O)[O-])C(=O)[O-].[Na+].[Na+]

• Molecular Formula:

  C20H19N5Na2O6

• Molecular Weight:

  471.37

• Shipping Conditions:

  Blue ice

• Storage Conditions:

  Store at -20°C.

• CAS Number:

  150399-23-8