Danusertib (PHA-739358)

• Description :

  Pan-aurora kinase inhibitor

• Product Name Alternative :

  N-[5-[(2R)-2-methoxy-2-phenylacetyl]-4,6-dihydro-1H-pyrrolo[3,4-c]pyrazol-3-yl]-4-(4-methylpiperazin-1-yl)benzamide

• Sequence :

  5-Amido-pyrrolopyrazole 9d

• Field of Research :

  Cell Cycle Checkpoint Aurora Kinase Chromatin Epigenetics Aurora Kinase Apoptosis c-RET Tyrosine Kinase c-RET Tyrosine Kinase FGFR

• Purity :

  0.9939

• Form :

  A solid

• Solubility :

  ≥23.75 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O

• Smiles :

  CN1CCN(CC1)C2=CC=C(C=C2)C(=O)NC3=NNC4=C3CN(C4)C(=O)C(C5=CC=CC=C5)OC

• Molecular Formula :

  C26H30N6O3

• Molecular Weight :

  474.55

• Shipping Conditions :

  Blue ice

• Storage Conditions :

  Store at -20°C.

• CAS Number :

  827318-97-8