Products for Research Use Only
RegisterLogin

AM1172

CAT: 0804-HY-103338-01Size: 5 mg (24.41 mM x 500 μL in Ethanol)Dry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-103338-01Size:5 mg (24.41 mM x 500 μL in Ethanol)
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
AM1172 is metabolically stable anandamide uptake inhibitor. AM1172 inhibits [3H] anandamide transport in rat cortical neurons and human CCF-STTG1 astrocytoma cells with IC50 values of 2.1 μM and 2.5 μM, respectively. AM1172 can significantly inhibit AEA hydrolysis and concurrently decrease AEA uptake. AM1172 can be used for the study of endocannabinoid system regulation[1][2][3].
CAS Number
251908-92-6
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/am1172.html
Concentration
24.41 mM * 1 mL in Ethanol
Purity
99.0
Solubility
10 mM in DMSO
Smiles
O=C(NCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)C1=CC=C(O)C=C1
Molecular Formula
C27H39NO2
Molecular Weight
409.60
References & Citations
[1]Fegley D, et al. Anandamide transport is independent of fatty-acid amide hydrolase activity and is blocked by the hydrolysis-resistant inhibitor AM1172. Proc Natl Acad Sci U S A. 2004 Jun 8;101 (23) :8756-61. |[2]Kaczocha M, et al. Anandamide uptake is consistent with rate-limited diffusion and is regulated by the degree of its hydrolysis by fatty acid amide hydrolase. J Biol Chem. 2006 Apr 7;281 (14) :9066-75.|[3]Fegley D, et al. Anandamide transport is independent of fatty-acid amide hydrolase activity and is blocked by the hydrolysis-resistant inhibitor AM1172. Proc Natl Acad Sci U S A. 2004 Jun 8;101 (23) :8756-61.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-177425AM11542
HY-128561AM12

Popular Products