Products for Research Use Only
RegisterLogin

SB-505124 hydrochloride

CAT: 0607-A3799-50Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0607-A3799-50Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
ALK5/ALK4/ALK7 inhibitor in TGF-β/activin signalling,selective
CAS Number
356559-13-2
Product Name Alternative
2-[4-(1,3-benzodioxol-5-yl)-2-tert-butyl-1H-imidazol-5-yl]-6-methylpyridine
Sequence
SB 505124 hydrochloride;SB505124 hydrochloride
Field of Research
TGF-β Smad Signaling TGF-βR1(ALK5)
Purity
0.98
Form
A solid
Solubility
insoluble in H2O; ≥87 mg/mL in EtOH; ≥9.3 mg/mL in DMSO
Smiles
CC1=CC=CC(=N1)C2=C(N=C(N2)C(C)(C)C)C3=CC4=C(C=C3)OCO4.Cl
Molecular Formula
C20H22ClN3O2
Molecular Weight
371.86
Shipping Conditions
Blue ice
Storage Conditions
Store at -20°C.

Chemical Information

2-(5-benzo(1,3)dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine hydrochloride

a selective inhibitor of transforming growth factor-beta type I receptors ALK4, ALK5, and ALK7

CAS Number356559-13-2
PubChem CID16079009
IUPAC Name2-[4-(1,3-benzodioxol-5-yl)-2-tert-butyl-1H-imidazol-5-yl]-6-methylpyridine;hydrochloride
Molecular FormulaC20H22ClN3O2
Molecular Weight371.9
Topological Polar Surface Area60
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Heavy Atom Count26
Formal Charge0
Complexity466
SMILES
CC1=NC(=CC=C1)C2=C(N=C(N2)C(C)(C)C)C3=CC4=C(C=C3)OCO4.Cl
InChI
InChI=1S/C20H21N3O2.ClH/c1-12-6-5-7-14(21-12)18-17(22-19(23-18)20(2,3)4)13-8-9-15-16(10-13)25-11-24-15;/h5-10H,11H2,1-4H3,(H,22,23);1H
InChIKey
BTUOOXPZOVNPMF-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 2-(5-benzo(1,3)dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine hydrochloride
CAS: 356559-13-2
CID: 16079009
Formula: C20H22ClN3O2
MW: 371.9
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight371.9
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Exact Mass371.1400546
Monoisotopic Mass371.1400546
Topological Polar Surface Area60 Ų
Heavy Atom Count26
Formal Charge0
Complexity466
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

Related Products

CatalogName
B6641-25SB 224289 hydrochloride
A3798-5.1SB-408124 Hydrochloride
B5334-5SB 258719 hydrochloride
B7309-5.1SB 399885 hydrochloride
A3798-10SB-408124 Hydrochloride
B7309-10SB 399885 hydrochloride
B1285-250SB 203580 hydrochloride
A3798-100SB-408124 Hydrochloride
B1285-5.1SB 203580 hydrochloride
B7309-5SB 399885 hydrochloride

Alternative Products

CatalogName
T21637-01SB-505124 hydrochloride
HY-13521A-01SB-505124 (hydrochloride)
sc-253542SB-505124 hydrochloride hydrate
A15232-50SB-505124 hydrochloride 50mg
HY-13521ARSB-505124 (hydrochloride) (Standard)
A15232-10SB-505124 hydrochloride 10mg
A15232-100SB-505124 hydrochloride 100mg
217779SB 242084 Hydrochloride (5-HT2C Receptor Antagonist, SB 242084 Hydrochloride, SB-242084 Hydrochloride, SB242084 Hydrochloride)
FS65160-01SB 271046 hydrochloride
FS27796SB 202190 hydrochloride

Popular Products