WZ4002

• Description:

  Mutant-selective EGFR inhibitor(L858R,T790M), irreversible and potent

• Product Name Alternative:

  N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

• Field of Research:

  JAK STAT Signaling EGFR Tyrosine Kinase EGFR

• Purity:

  0.9889

• Form:

  A solid

• Solubility:

  ≥24.7 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH

• Smiles:

  CN1CCN(CC1)C2=CC(=C(C=C2)NC3=NC=C(C(=N3)OC4=CC=CC(=C4)NC(=O)C=C)Cl)OC

• Molecular Formula:

  C25H27ClN6O3

• Molecular Weight:

  494.18

• Shipping Conditions:

  Blue ice

• Storage Conditions:

  Store at -20°C.

• CAS Number:

  1213269-23-8