WZ4002-hydroxy

• Target:

  Others

• Related Pathways:

  Others

• Bioactivity:

  WZ4002-hydroxyl is a WZ4002 derivative or WZ4002 analogue in which methoxy is replaced by hydroxyl and can be detected in 50% of patients with clinical resistance to gefitinib or erlotinib. WZ4002 has a basic chemical skeleton (covalent pyrimidine) that differs from other EGFR inhibitors.

• Smiles:

  C=CC (NC1=CC=CC (OC2=NC (NC3=CC=C (C=C3O) N4CCN (CC4) C) =NC=C2Cl) =C1) =O

• Molecular Formula:

  C24H25ClN6O3

• Molecular Weight:

  480.95

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C