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Cysteamine-d4 (hydrochloride)

CAT: 0804-HY-77591S-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-77591S-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cysteamine-d4 (hydrochloride) is the deuterium labeled Cysteamine hydrochloride. Cysteamine hydrochloride (2-Aminoethanethiol hydrochloride) is an orally active agent for the treatment of nephropathic cystinosis and an antioxidant.
CAS Number
1219805-04-5
Product Name Alternative
2-Aminoethanethiol-d4 (hydrochloride) ; 2-Mercaptoethylamine-d4 (hydrochloride)
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Autophagy; Endogenous Metabolite; Isotope-Labeled Compounds; Reactive Oxygen Species (ROS)
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis; Autophagy; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others
Field of Research
Metabolic Disease; Cancer
Purity
99.77
Solubility
10 mM in DMSO
Smiles
SC([2H])([2H])C([2H])([2H])N.Cl
Molecular Formula
C2H4D4ClNS
Molecular Weight
117.63
Precautions
H302, H315, H319, H335
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Besouw, M., et al., Cysteamine: an old drug with new potential. Drug Discov Today, 2013. 18 (15-16) : p. 785-92.|[3]de Matos, D.G., et al., Effect of cysteamine on glutathione level and developmental capacity of bovine oocyte matured in vitro. Mol Reprod Dev, 1995. 42 (4) : p. 432-6.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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