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Cysteamine (hydrochloride)

CAT: 0804-HY-77591-01Size: 10 gDry Ice: NoHazardous: No
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CAT#:0804-HY-77591-01Size:10 g
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Description
Cysteamine hydrochloride (2-Aminoethanethiol hydrochloride) is an orally active agent for the treatment of nephropathic cystinosis and an antioxidant.
CAS Number
156-57-0
Product Name Alternative
2-Aminoethanethiol (hydrochloride) ; 2-Mercaptoethylamine (hydrochloride)
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Autophagy; Endogenous Metabolite; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Apoptosis; Autophagy; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-Kinase/protease
Field of Research
Metabolic Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/Cysteamine-Hydrochloride.html
Purity
99.30
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : ≥ 50 mg/mL
Smiles
SCCN.Cl
Molecular Formula
C2H8ClNS
Molecular Weight
113.61
Precautions
H302, H315, H319, H335
References & Citations
[1]Besouw, M., et al., Cysteamine: an old drug with new potential. Drug Discov Today, 2013. 18 (15-16) : p. 785-92.|[2]de Matos, D.G., et al., Effect of cysteamine on glutathione level and developmental capacity of bovine oocyte matured in vitro. Mol Reprod Dev, 1995. 42 (4) : p. 432-6.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
Human Endogenous Metabolite

Chemical Information

Cysteamine Hydrochloride

Cysteamine hydrochloride is an alkanethiol.

CAS Number156-57-0
PubChem CID9082
IUPAC Name2-aminoethanethiol;hydrochloride
Molecular FormulaC2H8ClNS
Molecular Weight113.61
Topological Polar Surface Area27
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count2
Rotatable Bond Count1
Heavy Atom Count5
Formal Charge0
Complexity10
SMILES
C(CS)N.Cl
InChI
InChI=1S/C2H7NS.ClH/c3-1-2-4;/h4H,1-3H2;1H
InChIKey
OGMADIBCHLQMIP-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Cysteamine Hydrochloride
CAS: 156-57-0
CID: 9082
Formula: C2H8ClNS
MW: 113.61
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight113.61
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count2
Rotatable Bond Count1
Exact Mass113.0065981
Monoisotopic Mass113.0065981
Topological Polar Surface Area27 Ų
Heavy Atom Count5
Formal Charge0
Complexity10
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes