Guaiacol

• Description :

  Guaiacol, a phenolic compound, inhibits LPS-stimulated COX-2 expression and NF-κB activation[1]. Anti-inflammatory activity[1].

• Product Name Alternative :

  2-Methoxyphenol

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319

• Target :

  COX; Endogenous Metabolite; NF-κB

• Type :

  Natural Products

• Related Pathways :

  Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/Guaiacol.html

• Purity :

  99.95

• Solubility :

  DMSO : ≥ 100 mg/mL|H2O : 37.5 mg/mL (ultrasonic)

• Smiles :

  OC1=CC=CC=C1OC

• Molecular Formula :

  C7H8O2

• Molecular Weight :

  124.14

• Precautions :

  H302, H315, H319

• References & Citations :

  [1]Murakami Y, et al. Re-evaluation of cyclooxygenase-2-inhibiting activity of vanillin and Guaiacol in macrophages stimulated with lipopolysaccharide. Anticancer Res. 2007 Mar-Apr;27 (2) :801-7.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Natural Products

• Clinical Information :

  Launched

• Isoform :

  COX-2; NF-κB

• CAS Number :

  [90-05-1]