Guaiacol

• UNSPSC Description:

  Guaiacol, a phenolic compound, inhibits LPS-stimulated COX-2 expression and NF-κB activation[1]. Anti-inflammatory activity[1].

• Target Antigen:

  COX; Endogenous Metabolite; NF-κB

• Type:

  Natural Products

• Related Pathways:

  Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/Guaiacol.html

• Purity:

  99.73

• Solubility:

  DMSO : ≥ 100 mg/mL|H2O : 37.5 mg/mL (ultrasonic)

• Smiles:

  OC1=CC=CC=C1OC

• Molecular Weight:

  124.139

• References & Citations:

  [1]Murakami Y, et al. Re-evaluation of cyclooxygenase-2-inhibiting activity of vanillin and Guaiacol in macrophages stimulated with lipopolysaccharide. Anticancer Res. 2007 Mar-Apr;27(2):801-7.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  Launched

• CAS Number:

  90-05-1