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β-Elemonic acid

CAT: 0804-HY-N2454-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N2454-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
β-Elemonic acid is a triterpene isolated from Boswellia carterii. β-Elemonic acid induces cell apoptosis, reactive oxygen species (ROS) and COX-2 expression and inhibits prolyl endopeptidase. β-Elemonic acid exhibits anticancer and anti-inflammatory effects[1][2].
CAS Number
28282-25-9
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; COX; Endogenous Metabolite; Prolyl Endopeptidase (PREP) ; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/β-elemonic-acid.html
Purity
99.77
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : < 0.1 mg/mL
Smiles
C[C@@]12C3=C(CC[C@]1([C@@]([C@@H](C(O)=O)CC/C=C(C)/C)([H])CC2)C)[C@@]4([C@@](C(C)(C(CC4)=O)C)([H])CC3)C
Molecular Formula
C30H46O3
Molecular Weight
454.68
Precautions
H302, H315, H319, H335
References & Citations
[1]Atta-ur-Rahman, et al. Bioactive constituents from Boswellia papyrifera. J Nat Prod. 2005 Feb;68 (2) :189-93.|[2]Wu TT, et al. β-Elemonic acid inhibits the cell proliferation of human lung adenocarcinoma A549 cells: The roleof MAPK, ROS activation and glutathione depletion. Oncol Rep. 2016 Jan;35 (1) :227-34.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
COX-2

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Alternative Products

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A4633-10β-Elemonic acid
MBS5750210beta-Elemonic Acid
BUP03791-01SS-Elemonic Acid
A22403-100&beta; -Elemonic acid 100mg
A22403-50&beta; -Elemonic acid 50mg
A22403-500&beta; -Elemonic acid 500mg
A22403-25&beta; -Elemonic acid 25mg
A22403-5&beta; -Elemonic acid 5mg
A22403-10&beta; -Elemonic acid 10mg
A22403-1&beta; -Elemonic acid 1mg

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