EL-102

• Description:

  EL-102 is a hypoxia-induced factor 1 (Hif1α) inhibitor. EL-102 induces apoptosis, inhibits tubulin polymerisation and shows activities against prostate cancer. EL-102 can be used for the research of cancer[1].

• UNSPSC:

  12352005

• Target:

  Apoptosis; HIF/HIF Prolyl-Hydroxylase

• Type:

  Reference compound

• Related Pathways:

  Apoptosis; Metabolic Enzyme/Protease

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/EL-102.html

• Purity:

  99.44

• Solubility:

  DMSO : ≥ 36 mg/mL

• Smiles:

  O=S(C1=CC=C(OC)C=C1)(NC2=CC(C3=CSC(C#N)=C3)=CC=C2C)=O

• Molecular Formula:

  C19H16N2O3S2

• Molecular Weight:

  384.47

• References & Citations:

  [1]A P Toner et al. The novel toluidine sulphonamide EL102 shows pre-clinical in vitro and in vivoactivity against prostate cancer and circumvents MDR1 resistance. Br J Cancer, 2013 Oct 15, 109 (8) : 2131-2141.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [1233948-61-2]