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Tiglic acid

CAT: 0804-HY-W012999-01Size: 5 gDry Ice: NoHazardous: No
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CAT#:0804-HY-W012999-01Size:5 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tiglic acid is a monocarboxylic unsaturated organic acid. Tiglic acid can be isolated from croton oil. Tiglic acid agonizes FFA2 and upregulates PYY expression. Tiglic acid derivatives have anti-inflammatory activity. Tiglic acid can be used in the research of obesity, diabetes, and inflammatory diseases[1][2][3].
CAS Number
80-59-1
UNSPSC
12352211
Hazard Statement
H314
Target
Free Fatty Acid Receptor; Neuropeptide Y Receptor
Type
Natural Products
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tiglic-acid.html
Purity
99.98
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 5 mg/mL (ultrasonic)
Smiles
C/C=C(C)/C(O)=O
Molecular Formula
C5H8O2
Molecular Weight
100.12
Precautions
H314
References & Citations
[1]ROBERT E. BUCKLES, et al. THE PREPARATION OF TIGLIC AND ANGELIC ACIDS AND ESTERS. Cite This:J. Org. Chem.1950153680-684.|[2]Larraufie P, et al. SCFAs strongly stimulate PYY production in human enteroendocrine cells. Sci Rep. 2018 Jan 8;8 (1) :74. |[3]Wang HQ, et al. Hydroxylated Ethacrylic and Tiglic Acid Derivatives from the Stems and Branches of Enkianthus chinensis and Their Potential Anti-inflammatory Activities. J Nat Prod. 2020 Oct 23;83 (10) :2867-2876.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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