USP10-IN-3

• UNSPSC Description:

  USP10-IN-3 (compound D1) is a potent USP10 inhibitor with an IC50 value of 7.2 µM. USP10-IN-3 inhibits cell proliferation. USP10-IN-3 induces apoptosis and cell cycle arrest at S-phase[1].

• Target Antigen:

  Apoptosis

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/usp10-in-3.html

• Solubility:

  DMSO : 5 mg/mL (ultrasonic)

• Smiles:

  CC1=CC=C2C(C(C3=NC(C4=C(C=CC=C4)C)=NO3)=CN(C2=C1)CC(NCCC5=CC=C(C=C5)Cl)=O)=O

• Molecular Weight:

  512.99

• References & Citations:

  [1]Lu Y, et al. Discovery of potent small molecule ubiquitin-specific protease 10 inhibitors with anti-hepatocellular carcinoma activity through regulating YAP expression. Eur J Med Chem. 2024 Jun 5;272:116468.

• Shipping Conditions:

  Blue Ice

• Clinical Information:

  No Development Reported

• CAS Number:

  3059565-11-3