8-Pcpt-cGMP

CAT: 0804-HY-137016Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-137016Size:1 Each

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Description

8-Pcpt-cGMP is an agonist for cyclic nucleotide-gated (CNG) channel with an EC50 of 0.5 μM. 8-Pcpt-cGMP exhibits good membrane permeability. 8-Pcpt-cGMP can be used in studies about the function of CNG channels in visual signal transduction and olfactory transduction[1].

CAS Number

54364-02-2

UNSPSC

12352005

Target

HCN Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/8-pcpt-cgmp.html

Smiles

O[C@H]1[C@](O[C@@](CO2)([H])[C@@]1([H])O[P]2(O)=O)([H])N3C(NC(N)=NC4=O)=C4N=C3SC(C=C5)=CC=C5Cl

Molecular Formula

C16H15ClN5O7PS

Molecular Weight

487.81

References & Citations

[1]Wei JY, et al., Substituted cGMP analogs can act as selective agonists of the rod photoreceptor cGMP-gated cation channel. J Mol Neurosci. 1998 Feb;10 (1) :53-64.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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GTR19236336-01	8-Pcpt-cGMP
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8-Pcpt-cGMP

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