(+)-LRH-1 modulator-1

(+)-LRH-1 modulator-1

• UNSPSC Description: (+)-LRH-1 modulator-1 is a stereoisomer of LRH-1 modulator-1. LRH-1 modulator-1 (compound 6N) is a potent LRH-1 (liver receptor homolog-1) modulator/agonist. LRH-1 modulator-1 has anti-inflammatory effects in intestinal organoids. LRH-1 modulator-1 induces the anti-inflammatory cytokine IL-10 and reduces the inflammatory cytokines IL-1b and TNFa[1].
• Target Antigen: Interleukin Related
• Type: Reference compound
• Related Pathways: Immunology/Inflammation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/plus-lrh-1-modulator-1.html
• Smiles: C=C(C1=CC=CC=C1)[C@]([C@](C2)([H])[C@H]3N[S](N)(=O)=O)(CC3)C(C4=CC=CC=C4)=C2CCCCCC
• Molecular Weight: 464.66
• References & Citations: [1]Mays S G, et al. Development of the first low nanomolar liver receptor homolog-1 agonist through structure-guided design[J]. Journal of medicinal chemistry, 2019, 62(24): 11022-11034.
• Shipping Conditions: Blue Ice
• Clinical Information: No Development Reported