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(-) -Hinesol

CAT: 0804-HY-N1930-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N1930-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(-) -Hinesol (Hinesol) is a potent anticancer agent. (-) -Hinesol induces apoptosis and cell cycle arrest at G0/G1 phase. (-) -Hinesol downregulates MEK/ERK pathway and NF-κB pathway and mediates theexpression of cyclin D1, Bax and Bcl-2. (-) -Hinesol has the potential for the research of non–small cell lung cancer[1].
CAS Number
23811-08-7
Product Name Alternative
Hinesol
UNSPSC
12352211
Target
Apoptosis
Type
Natural Products
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/minus-hinesol.html
Purity
98.7
Solubility
10 mM in DMSO
Smiles
C[C@@H]1[C@]2(C[C@H](C(O)(C)C)CC2)C(C)=CCC1
Molecular Formula
C15H26O
Molecular Weight
222.37
References & Citations
[1]Guo W, et al. The antitumor effect of hinesol, extract from Atractylodes lancea (Thunb.) DC. by proliferation, inhibition, and apoptosis induction via MEK/ERK and NF-κB pathway in non-small cell lung cancer cell lines A549 and NCI-H1299. J Cell Biochem. 2019 Nov;120 (11) :18600-18607.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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