TLR7 agonist 1

TLR7 agonist 1

• CAS Number: 2178156-33-5
• UNSPSC Description: TLR7 agonist 1 is a potent, selective and oral TLR7 agonist with an IC50 of 90 nM.
• Target Antigen: Toll-like Receptor (TLR)
• Type: Reference compound
• Related Pathways: Immunology/Inflammation
• Applications: COVID-19-immunoregulation
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/TLR_7_agonist_1.html
• Purity: 98.95
• Solubility: DMSO : ≥ 100 mg/mL
• Smiles: NC1=NC2=C(C(C(N[C@@H](C)C3=CC=CC=C3)=O)=CC=C2)C(NCCCC)=N1
• Molecular Weight: 363.46
• References & Citations: [1]Pieters S, et al. Discovery of selective 2,4-diaminoquinazoline toll-like receptor 7 (TLR 7) agonists. Bioorg Med Chem Lett. 2018 Feb 15;28(4):711-719.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported