CKD-519
CAT:
804-HY-116078-04
Size:
10 mM / 1 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
CKD-519
- CAS Number: 1402796-27-3
- UNSPSC Description: CKD-519 is a selective and potent cholesteryl ester transfer protein (CETP) inhibitor, which inhibits CETP-mediated transfer of cholesteryl ester in human serum with an IC50 of 2.3 nM[1].
- Target Antigen: CETP
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Field of Research: Cardiovascular Disease
- Assay Protocol: https://www.medchemexpress.com/ckd-519.html
- Purity: 99.65
- Solubility: DMSO : 66.67 mg/mL (ultrasonic)
- Smiles: C[C@H]1[C@H](OC(N1CC2=C(C3=C(C=C(C(C(C)C)=C3)F)OC)CCC(C)(C2)C)=O)C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4
- Molecular Weight: 601.60
- References & Citations: [1]Kim CO, et al. Pharmacokinetics, pharmacodynamics and safety of CKD-519, a CETP inhibitor, in healthy subjects. Drug Des Devel Ther. 2016 Nov 15;10:3763-3770.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: Phase 2