Desloratadine (Standard)
CAT:
804-HY-B0539R-02
Size:
25 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Desloratadine (Standard)
- CAS Number: 100643-71-8
- UNSPSC Description: Desloratadine (Standard) is the analytical standard of Desloratadine. This product is intended for research and analytical applications. Desloratadine (Sch34117) is the orally active major metabolite of the nonsedating H1-antihistamine Loratadine. Desloratadine is a selective H1-receptor antagonist that has anti-allergic and anti-inflammatory activities[1][2].
- Target Antigen: Drug Metabolite; Endogenous Metabolite; Histamine Receptor
- Type: Reference Standards
- Related Pathways: GPCR/G Protein;Immunology/Inflammation;Metabolic Enzyme/Protease;Neuronal Signaling
- Field of Research: Inflammation/Immunology; Endocrinology; Cancer
- Assay Protocol: https://www.medchemexpress.com/desloratadine-standard.html
- Solubility: 10 mM in DMSO
- Smiles: ClC1=CC=C2C(CCC3=CC=CN=C3/C2=C4CCNCC/4)=C1
- Molecular Weight: 310.82
- References & Citations: [1]McClellan K, et al. Desloratadine. Drugs. 2001;61(6):789-797.|[2]Geha, R.S. and E.O. Meltzer, Desloratadine: A new, nonsedating, oral antihistamine. J Allergy Clin Immunol, 2001. 107(4): p. 751-62.|[3]Schroeder, J.T., et al., Inhibition of cytokine generation and mediator release by human basophils treated with desloratadine. Clin Exp Allergy, 2001. 31(9): p. 1369-77.|[4]Anthes, J.C., et al., Biochemical characterization of desloratadine, a potent antagonist of the human histamine H(1) receptor. Eur J Pharmacol, 2002. 449(3): p. 229-37.
- Shipping Conditions: Room temperature
- Clinical Information: Launched