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S-312-d

CAT: 0804-HY-105271Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-105271Size:1 Each
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Description
S-312-d (S- (+) -S-312-d) is a calcium channel blocker with the activity of protecting the kidney from ischemic acute renal failure. S-312-d (0.01-0.1mg/kg b.wt. iv) administered before ischemia has a dose-dependent protective effect on ischemia-induced renal damage, improves the survival rate of ischemic rats, and reduces renal cortical edema and the increase in renal tissue calcium content.
CAS Number
120056-57-7
Product Name Alternative
S- (+) -S-312-d
UNSPSC
12352005
Target
Calcium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/s-312-d.html
Smiles
CC(CC1=CSC2=C1[C@H](C(C(OC)=O)=C(N2)C)C3=CC([N+]([O-])=O)=CC=C3)C
Molecular Formula
C20H22N2O4S
Molecular Weight
386.46
References & Citations
[1]Studies on dihydropyridines. III. Synthesis of 4,7-dihydrothieno [2,3-b]-pyridines with vasodilator and antihypertensive activities|[2]Protective effect of a novel calcium blocker, S-312-d, on ischemic acute renal failure in rat
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2

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