Products for Research Use Only
RegisterLogin

ICOS-IN-1

CAT: 0804-HY-162810Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-162810Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
ICOS-IN-1 (compound 9) is an inhibitor of the interaction between ICOS and ICOS-L (IC50=29.38 μM) and has activity in recognizing immune checkpoints[1].
CAS Number
1006002-58-9
UNSPSC
12352101
Target
CD28
Type
Reference compound
Related Pathways
Immunology/Inflammation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/icos-in-1.html
Smiles
OC1=C(C2=NNC=C2)C=CC(OCC3=CC=C(Cl)C(Cl)=C3)=C1C
Molecular Formula
C17H14Cl2N2O2
Molecular Weight
349.21
References & Citations
[1]Longfei Zhang, et al. "Discovery of ICOS-targeted small molecules using affinity selection mass spectrometry screening." bioRxiv (2024) : 2024-08.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-P78307ICOS, Mouse (HEK293, Fc)
HY-P72619-01ICOS, Mouse (HEK293, His)
HY-P86912-01ICOS Antibody (YA6605, Rabbit)
HY-P81467-01ICOS Antibody (YA1212, Rabbit)
HY-P84984ICOS Antibody (YA4676, Mouse)
HY-P72618-01ICOS, Human (HEK293, Fc)
HY-P74868-01ICOS, Rat (HEK293, Fc)
HY-W011267-01(Z) -Methyl icos-11-enoate
HY-P76396ICOS, Human (HEK293, His-Fc)
HY-P70187ICOS, Rhesus Macaque (HEK293, Fc)

Alternative Products

CatalogName
T200361-01ICOS-IN-1
GTR18574579ICOS Ligand Antibody / ICOS-L / B7RP-1
583189ICOS
MBS4380902-01ICOS-L/ICOS Ligand/B7RP-1 (Immuno-Oncology Target)
GTR18156508ICOS Antibody
MBS2889241ICOS ligand
sc-53698ICOS (15F9)

Popular Products