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(R) - (+) -Aminoglutethimide

CAT: 0804-HY-W392925-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W392925-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(R) - (+) -Aminoglutethimide is a potent and orally active aromatase inhibitor. (R) - (+) -Aminoglutethimide has the potential for the research of breast cancer[1].
CAS Number
55511-44-9
Product Name Alternative
D-Aminoglutethimide
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Cytochrome P450
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/r-plus-aminoglutethimide.html
Purity
97.08
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 4.17 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C([C@@](CC)(C1=CC=C(N)C=C1)CC2)NC2=O
Molecular Formula
C13H16N2O2
Molecular Weight
232.28
Precautions
H315, H319, H335
References & Citations
[1]Dai Sig Im, et al. Chemo-enzymatic synthesis of (R) - (+) -aminoglutethimide by kinetic resolution of (±) -4-cyano-4-phenyl-1-hexanol. Journal of Molecular Catalysis B: Enzymatic. 2003, 26:185–191.|[2]Egger H, Bartlett F, Itterly W, Rodebaugh R, Shimanskas C. Metabolism of aminoglutethimide in the rat. Drug Metab Dispos. 1982 Jul-Aug;10 (4) :405-12.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
Aromatase/CYP19A1

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