Endomorphin 2

CAT: 0931-T7218-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0931-T7218-01Size:1 mg

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CAS Number

141801-26-5

Target

Opioid Receptor

Related Pathways

Neuroscience, Endocrinology/Hormones, GPCR/G Protein

Purity

0.9964

Bioactivity

Endomorphins-2 (EM-2) could decrease both the frequency and amplitude of the sEPSC of the motoneurons in lamina IX, which was reversed by the MOR antagonist CTOP. EM-2-IR fibers originated from primary afferent fibers form symmetric synaptic connections with motoneurons innervating skeletal muscles of the lower limbs in lamina IX of the spinal ventral horn and EM-2 might exert inhibitory effects on the activities of these motoneurons through both presynaptic and postsynaptic mechanisms.

Smiles

C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC2=CC=CC=C2)C(N)=O)=O)(=O)[C@H]3N(C([C@H](CC4=CC=C(O)C=C4)N)=O)CCC3

Molecular Formula

C32H37N5O5

Molecular Weight

571.67

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

Endomorphin 2

isolated from bovine brain

CAS Number	141801-26-5
PubChem CID	5311081
IUPAC Name	(2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]pyrrolidine-2-carboxamide
Molecular Formula	C32H37N5O5
Molecular Weight	571.7
XLogP	2.3
Topological Polar Surface Area	168
Hydrogen Bond Donor Count	5
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	12
Heavy Atom Count	42
Formal Charge	0
Complexity	911

SMILES

C1C[C@H](N(C1)C(=O)[C@H](CC2=CC=C(C=C2)O)N)C(=O)N[C@@H](CC3=CC=CC=C3)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)N

InChI

InChI=1S/C32H37N5O5/c33-25(18-23-13-15-24(38)16-14-23)32(42)37-17-7-12-28(37)31(41)36-27(20-22-10-5-2-6-11-22)30(40)35-26(29(34)39)19-21-8-3-1-4-9-21/h1-6,8-11,13-16,25-28,38H,7,12,17-20,33H2,(H2,34,39)(H,35,40)(H,36,41)/t25-,26-,27-,28-/m0/s1

InChIKey

XIJHWXXXIMEHKW-LJWNLINESA-N

Chemical Structure

2D Structure

CAS: 141801-26-5

CID: 5311081

Formula: C32H37N5O5

MW: 571.7

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	571.7
XLogP3	2.3
Hydrogen Bond Donor Count	5
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	12
Exact Mass	571.27946930
Monoisotopic Mass	571.27946930
Topological Polar Surface Area	168 Å²
Heavy Atom Count	42
Formal Charge	0
Complexity	911
Isotope Atom Count	0
Defined Atom Stereocenter Count	4
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

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T125691-01	2-[2- (2,2,2-Trifluoroethoxy) phenoxy]ethyl bromide
T9894-01	2-[2- (2,2,2-Trifluoroethoxy) phenoxy]ethyl methanesulfonate
TN9630-01	2,2':6',2''-Terpyridine
T5650-01	2,2':5',2''-Terthiophene

Alternative Products

Catalog	Name
4027684.0025	Endomorphin-1
H-4004.0005	Endomorphin-2
448211-01	Endomorphin 1
GTR19157376-01	Endomorphin 2?
E2291-25C	Endomorphin 2

Endomorphin 2

Chemical Information

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